NANoREG D2 10 SOP 04

NANoREG D4 04 DR Organ burden and particle detection pattern in other organs after subacute exposure

Acesse:

https://www.rivm.nl/en/documenten/nanoreg-d4-04-dr-organ-burden-and-particle-detection-pattern-in-other-organs-after 

NANoREG D4.02 DR Provide histological samples from chronic study

Acesse:

https://www.rivm.nl/documenten/nanoreg-d402-dr-provide-histological-samples-from-chronic-study 

NANoREG D2.10 SOP 05 Electron microscopic image analysis of primary particles in aggregated nanomaterials

Acesse:

https://www.rivm.nl/en/documenten/nanoreg-d210-sop-05-electron-microscopic-image-analysis-of-primary-particles-in

NANoREG D6 03 DR Comparison on toxicity testing in drug development and in present MNMs safety testing

Acesse:

https://www.rivm.nl/en/documenten/nanoreg-d6-03-dr-comparison-on-toxicity-testing-in-drug-development-and-in-present-mnms

NANoREG D4.18 DR Overall evaluation of data, publication, and transfer to OECD sponsorship programme

Acesse:

https://www.rivm.nl/documenten/nanoreg-d418-dr-overall-evaluation-of-data-publication-and-transfer-to-oecd-sponsorship 

NANoREG D2.04 DR Protocol for quantitative analysis of inorganic MNM surface coatings

Acesse:

https://www.rivm.nl/en/documenten/nanoreg-d2-04-dr-protocol-for-quantitative-analysis-of-inorganic-mnm-surface-coatings

SOPs available in Deliverable Report

• SOP for determination of organic content in MNMs by thermogravimetric analysis (TGA)
• SOP for assessment of the contents of water, organic compounds, and degradable inorganics in MNMs using a drying oven and a laboratory furnace
• SOP for determination of inorganic content in MNMs by Wavelength dispersive X-ray fluorescence (WDXRF)
• SOP for characterization of non-covalent bound organic surface coating on MNM by extraction and mass spectrometry
• SOP for determination of inorganic coating in MNMs by Transmission Electron Microscopy
• SOP for determination of oxygen containing functional groups on CNT by decarbonylisation,  decarboxylation, and dehydration in inert atmosphere using TGA-MS