NANoREG D5 07 SOP 17

NANoREG D5 08 DR Decision tree for risk assessment of MNMs

Acesse:

https://www.rivm.nl/en/documenten/nanoreg-d5-08-dr-decision-tree-for-risk-assessment-of-mnms 

RIVM FlowChart NANoREG nanospecific risk assessment strategy

NANoREG D5.03 DR In vitro screening methodology for absorption or crossing of other barriers

Acesse:

https://www.rivm.nl/en/documenten/nanoreg-d503-dr-in-vitro-screening-methodology-for-absorption-or-crossing-of-other 

SOPs available in deliverable:

• SOP 01 Protocol for organotypic cell culture modified for exposure to nanomaterials
• SOP 02 Caco-2 cell culture and differentiation
• SOP 03 Evaluation of NMs impact on Caco-2 cell barrier model

NANoREG D2.08 SOP 07 For determination of LDH, IL-6, IL-8 adsorption onto MNM

Acesse:

https://www.rivm.nl/en/documenten/nanoreg-d208-sop-07-for-determination-of-ldh-il-6-il-8-adsorption-onto-mnm 

NANoREG D6 03 DR Comparison on toxicity testing in drug development and in present MNMs safety testing

Acesse:

https://www.rivm.nl/en/documenten/nanoreg-d6-03-dr-comparison-on-toxicity-testing-in-drug-development-and-in-present-mnms

NANoREG D2.11 DR Protocol(s) for VSSA analysis of primary MNM in objects air, powders, and liquids for compliance with the EU definition

Acesse:

https://www.rivm.nl/en/documenten/nanoreg-d211-dr-protocols-for-vssa-analysis-of-primary-mnm-in-objects-air-powders-and

NANoREG D4 12 DR Accumulation potential and aquatic toxicity of relevant groups of nanomaterials and product formula

Acesse:

https://www.rivm.nl/en/documenten/nanoreg-d4-12-dr-accumulation-potential-and-aquatic-toxicity-of-relevant-groups-of 

SOPs available in Deliverable:

• SOP 01 Toxicity Test with Daphnia magna for NANoREG core nanomaterials
• SOP 02 Toxicity Test with Microalgae Pseudokirchneriella subcapitata
• SOP 03 Toxicity test with the nematode Caenorhabditis elegans
• SOP 04 Fish, Acute Toxicity Test

Extra SOP developed within WP2 for ecotoxicological testing:

NANoREG D4.12 SOP Probe Sonicator Calibration for ecotoxicological testing